Lance Wells Selected Research

N-acetylglucosaminono-1,5-lactone O-(phenylcarbamoyl)oxime (PUGNAC)

11/2016	Dissecting PUGNAc-mediated inhibition of the pro-survival action of insulin.
4/2002	Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes.

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Lance Wells Research Topics

Disease

12	Muscular Dystrophies (Muscular Dystrophy) 10/2017 - 01/2010
9	Insulin Resistance 11/2016 - 04/2002
7	Neoplasms (Cancer) 01/2021 - 04/2008
5	Infections 01/2022 - 01/2019
4	Intellectual Disability (Idiocy) 01/2021 - 01/2017
4	Hyperglycemia 01/2016 - 04/2002
2	Inflammation (Inflammations) 01/2022 - 03/2008
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 03/2008
2	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 01/2020 - 01/2016
2	Adenocarcinoma 02/2014 - 02/2010
2	Type 2 Diabetes Mellitus (MODY) 01/2014 - 02/2007
2	Obesity 01/2014 - 03/2008
2	Walker-Warburg Syndrome 08/2012 - 01/2010
2	Breast Neoplasms (Breast Cancer) 07/2012 - 04/2008
2	Ovarian Neoplasms (Ovarian Cancer) 02/2010 - 07/2008
1	Human Influenza (Influenza) 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	COVID-19 07/2020
1	Galactosemias (Galactosemia) 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2016
1	Acute Erythroblastic Leukemia (Erythroleukemia) 02/2016
1	Diabetes Mellitus 12/2014
1	Metabolic Diseases (Metabolic Disease) 03/2014
1	Heart Diseases (Heart Disease) 03/2014
1	Pancreatic Neoplasms (Pancreatic Cancer) 02/2014
1	Pancreatitis 02/2014
1	Neoplasms, Cystic, Mucinous, and Serous 02/2014
1	Hyperinsulinism (Hyperinsulinemia) 01/2014
1	Pathologic Processes 01/2013
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 06/2012
1	Neoplasm Metastasis (Metastasis) 10/2011
1	Diabetic Nephropathies (Diabetic Nephropathy) 09/2011
1	Hemorrhage 05/2010
1	Wounds and Injuries (Trauma) 05/2010
1	Adenoma (Adenomas) 02/2010
1	Carcinogenesis 04/2008
1	Hypertension (High Blood Pressure) 03/2008
1	Diabetes Complications 02/2007
1	Alzheimer Disease (Alzheimer's Disease) 09/2004

Drug/Important Bio-Agent (IBA)

25	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2002
10	Dystroglycans (Dystroglycan)IBA 01/2022 - 03/2010
8	Polysaccharides (Glycans)IBA 02/2016 - 04/2008
6	Glycoproteins (Glycoprotein)IBA 01/2021 - 04/2008
6	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2008
6	Insulin (Novolin)FDA Link 01/2016 - 04/2002
6	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 04/2002
6	GlycosyltransferasesIBA 01/2016 - 04/2008
5	Mannose (D-Mannose)IBA 01/2022 - 01/2010
5	EnzymesIBA 04/2021 - 10/2011
5	O-GlcNAc transferaseIBA 01/2021 - 02/2007
4	AcetylglucosamineIBA 01/2017 - 01/2014
4	AdipokinesIBA 01/2014 - 03/2008
3	LigandsIBA 01/2022 - 06/2011
3	AntibodiesIBA 01/2021 - 07/2008
3	HexosaminesIBA 01/2014 - 04/2002
2	Laminin (Merosin)IBA 01/2022 - 01/2010
2	SialyltransferasesIBA 01/2022 - 02/2016
2	Monoclonal AntibodiesIBA 01/2019 - 05/2010
2	N-acetylglucosaminono-1,5-lactone O-(phenylcarbamoyl)oxime (PUGNAC)IBA 11/2016 - 04/2002
2	ProteomeIBA 02/2014 - 03/2008
2	LectinsIBA 02/2010 - 04/2008
1	DisaccharidesIBA 01/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	SuspensionsIBA 04/2021
1	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 01/2021
1	Biological ProductsIBA 01/2021
1	Cell Surface ReceptorsIBA 07/2020
1	NucleotidesIBA 01/2020
1	Death Domain ReceptorsIBA 01/2020
1	VaccinesIBA 01/2019
1	Amino Acids FDA Link 01/2017
1	ErbB Receptors (EGF Receptor)IBA 12/2016
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 12/2016
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 12/2016
1	dolichyl-diphosphooligosaccharide - protein glycotransferase (oligosaccharyltransferase)IBA 12/2016
1	Acetylglucosaminidase (NAGase)IBA 11/2016
1	SialoglycoproteinsIBA 02/2016
1	poly-N-acetyllactosamineIBA 10/2014
1	ChromatinIBA 03/2014
1	Membrane Proteins (Integral Membrane Proteins)IBA 07/2012
1	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 07/2012
1	GPI-Linked ProteinsIBA 07/2012
1	DystrophinIBA 06/2012
1	AcetylgalactosamineIBA 06/2012
1	MucinsIBA 06/2012
1	ActininIBA 09/2011
1	PeriostinIBA 02/2010
1	ThrombospondinsIBA 02/2010
1	Blood Proteins (Serum Proteins)IBA 07/2008
1	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase)IBA 04/2008
1	AngiotensinsIBA 03/2008
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 03/2008
1	hippocampal cholinergic neurostimulating peptideIBA 03/2008
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 03/2008
1	Phosphates (Orthophosphate)IBA 09/2004
1	Insulin Receptor Substrate ProteinsIBA 04/2002

Therapy/Procedure

1	Therapeutics 01/2021
1	Organ Transplantation 01/2019
1	Blood Transfusion (Blood Transfusions) 01/2019
1	Resuscitation 05/2010